Week 1 2023 NFL football knockout, survivor pool, strategy, and advice: The 49ers fade.

SportsLine's powerful computer model picked the best Week 1 NFL survivors. Three NFL rookie quarterbacks will debut in Week 1.

Carolina Panthers No. 1 selection Bryce Young will lead them against Atlanta Falcons in NFC South game. 

Anthony Richardson and the Indianapolis Colts face the Jacksonville Jaguars, while C.J. Stroud and the Houston Texans visit the Ravens. 

 The Panthers are 3.5-point underdogs on the road and the Colts are +4.5 at home in Week 1, making NFL knockout pool choices difficult. 

The Week 1 NFL spreads' biggest underdogs are the Texans (+10).

Should you choose a rookie QB team in your NFL survival pool or seek elsewhere.

 See which team the hot SportsLine Projection Model bet on before making Week 1 NFL survival selections.

The algorithm, which simulates every NFL game 10,000 times, has earned over $7,000 for $100 players on top NFL choices since its start.


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